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As with autoimmunity, BSOs ability to balance and regulate the immune system is one of the main reasons its so effective for these allergic atopic conditions

Activated mast cells can trigger microglial activation via the release of histamine, prostaglandins, and protease-activated receptor ligands (Zhang et al., 2016)

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Neurology 67 , 14111420 (2006)

Clinically, non-steroidal anti-inflammatory drugs (NSAIDs) for the treatment of RA are achieved by inhibiting COX to inhibit the expression of PGE2

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